9 BEST PROBIOTIC BACTERIA
9 high-potency live hardy strains
Research at the University of Nebraska and Nebraska Cultures now shows that certain strains developed there meet the strict criteria for effectiveness.
Two strains in particular give an outstanding performance. Added to those are 7 other viable hardy strains with particular properties.
Probiotic Strain 1: B. coagulans
Bacillus coagulans ProDURA™ is a unique endospore bacterium strain which is encased in an outer shell, allowing it to withstand the harsh environment of the gut. It has been shown to remain potent even at room temperature for 3 years, and can survive temperatures of up to 100°.
When these bacteria encounter the ideal conditions of temperature, pH, and moisture in the large intestine, they revert to their active form.
Human and in vitro research (refs) shows B. coagulans bacteria:
- Support a healthy balance of beneficial to harmful bacteria
- Support the health of the vaginal and gastrointestinal tracts
- Helps break down lactose
- Help maintain cholesterol levels already within a normal range
Probiotic Strain 2: L. acidophilus
Lactobacillus acidophilus DDS-1 is manufactured with unique stabilisers that confer proven persistence in the gut (see reference below). It produces acidophilin, a natural antibiotic compoud and helps produce vitamins B6, B12 and folic acid. Like Bacillus coagulans, it also helps suppress pathogenic bacteria such as H. pylori, E. coli, Psudeomonas, and S. aureus.
A randomised, double blind, placebo controlled crossover clinical trial showed that Lactobacillus acidophilus DDS-1 confers statistically significant relief in the case of lactose intolerance.
Probiotic Strain 3: B. lactis
Bifidobacterium lactis is a lactic acid bacterium that can help fight lactose intolerance, support the immune system and reduce the occurrence of antibiotic-associated diarrhoea.
According to the American Society for Microbiology, B. lactis has beneficial microorganisms that help with the elimination of toxic waste in the colon and thus help combat colitis – inflammation of the colon.
Bifidobacterium may also help relief constipation when consumed over a 3-6 week period.
Probiotic Strain 4: L. casei
Lactobacillus casei is documented to have a wide pH and temperature tolerance, and complements the growth of L. acidophilus, a producer of the enzyme amylase – itself a carbohydrate-digesting enzyme.
There is research evidence that L. casei may reduce the risk and symptoms of IBS, and inhibit H.pylori, the harmful bacteria that can precipitate ulcers. It helps reduce allergenic responses and inhibits and reduces diarrhoea episodes.
A small double-blind study Japanese study on L. casei showed that HDL cholesterol (the good kind) was much significantly higher in the probiotic supplement group compared to the placebo group, and triglyceride levels also decreased.
Probiotic Strain 5: L. rhamnosus
Lactobacillus rhamnosus has been used to prevent diarrhoea and to lessen the effect of seasonal allergies, particularly hay fever. It may also help lessen the effect of irritable bowel syndrome and reduce vaginal infections caused by bacteria.
Probiotic Strain 6: L. plantarum
Lactobacillus plantarum is a probiotic found in the Korean food kimchi and in sauerkraut. Studies show that L. plantarum is resistant to most antibiotics – which is important as antibiotics can cause serious yeast overgrowth. L. plantarum shows benefit against IBS and gut inflammation.
Probiotic Strain 7: S. thermophilus
Streptococcus thermophilus is mostly found in the colon. Also known as Streptococcus salivarius thermophilus, the last part of its denomination – thermophilus – refers to this strain’s capacity to withstand higher temperatures, making it a particularly resistant probiotic.
It is known to produces antibiotic compounds that help prevent infection from pathogens and bacteria like pneumonia, and C. difficile. It has also been researched to help reduce the risk of ulcers and may help in cases of IBS.
Probiotic Strain 8: B. longum
Bifidobacterium longum. Clinical data shows that B. longum – also known as B. infantis – supports immune function. It has been shown to increase Natural Killer cell activity. In particular, B. longum has been shown to help lower the incidence of respiratory tract infections and flu.
Other research indicates that B. longum can ‘significantly’ decrease enterotoxins (intestinal toxins) that are associated with gut inflammation and inflammatory bowel disease. Additional studies confirm that B. longum may suppress IgE levels – a key marker of allergic response.
Finally, B. longum is a strain that has been shown, in animal studies, to help reduce LDL cholesterol.
Probiotic Strain 9: B. bifidum
Bifidobacterium bifidum. Levels of B. bifidum decline with age. It is a probiotic that helps improve the immune system and reduce general infections from pathogens. It has been shown to reduce the severity of irritable bowel syndrome, and of diarrhoea – especially when combined with L. rhamnosus.
Studies show that it also combines well with B. lactis and L. acidophilus to help people with IBS. B. bifidum may also improve blood sugar control and reduce stress.
Tolerance of acid and bile
The results for all 9 strains in MicroBiotic Plus, selected for their synergistic effect, are:
- Lomax AR, Calder PC. Probiotics, immune function, infection and inflammation: a review of the evidence from studies conducted in humans. Curr Pharm Des. 2009;15(13):1428-518.
- Donskey CJ, et al. Lett Appl Microbiol. 2001 Jul;33(1):84-8.
- K Lindfors, T Blomqvist, K Juuti-Uusitalo, et al. Live probiotic Bifidobacterium lactis bacteria inhibit the toxic effects induced by wheat gliadin in epithelial cell culture. Clin Exp Immunol. 2008 Jun; 152(3): 552-558. doi: 10.1111/j.1365-2249.2008.03635.x.
- Jain PK, McNaught CE, Anderson AD, MacFie J, Mitchell CJ. Influence of synbiotic containing Lactobacillus acidophilus La5, Bifidobacterium lactis Bb 12, Streptococcus thermophilus, Lactobacillus bulgaricus and oligofructose on gut barrier function and sepsis in critically ill patients: a randomised controlled trial. Clin Nutr. 2004 Aug;23(4):467-75.
- Saavedra JM, Bauman NA, Oung I, Perman JA, Yolken RH. Feeding of Bifidobacterium bifidum and Streptococcus thermophilus to infants in hospital for prevention of diarrhoea and shedding of rotavirus. Lancet. 1994 Oct 15;344(8929):1046-9
- Sudha RM, Radkar N, Maurya A. Int J Probiotic Prebiotics. 2011 May;6(2):1-5
- Beneficial effects of Probiotic consumption on the Immune System. Maldonado Galdeano C et al: Ann Nutr Metab 2019;74:115–124
- Effect of Probiotics on Depression: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Ruixue Huang, Ke Wang and Jianan Hu: Nutrients 2016
- Clinical Effects of Probiotic Bifidobacterium Longum BB536 on Immune Function and Intestinal Microbiota in Elderly Patients Receiving Enteral Tube Feeding. Hiroyasu Akatsu, Noriyuki Iwabuchi, Jin-Zhong Xiao, Zenjiro Matsuyama, Rina Kurihara, Kenji Okuda, Takayuki Yamamoto, Mitsuo Maruyama; J Parenter Enteral Nutr 2013
- Effects of Bifidobacterium Longum BB536 Administration on Influenza Infection, Influenza Vaccine. Kazuyoshi Namba 1, Michiko Hatano, Tomoko Yaeshima, Mitsunori Takase, Kunihiko Suzuki; Biosci Biotechnol Biochem 2010
- Randomized controlled trial of live lactobacillus acidophilus plus bifidobacterium bifidum in prophylaxis of diarrhea during radiotherapy in cervical cancer patients. Imjai Chitapanarux, Radiat Oncol. 2010; 5: 31.